Moreno Herrero Lab
Molecular Biophysics of DNA repair nanomachines
Centro Nacional de Biotecnologia (CSIC)
Lab. B17/B18
C/Darwin 3, Campus de Cantoblanco 28049 Madrid, Spain
Publications | Thesis | Press
54) Martín-García B., Martín-González A, et al. Nucleic Acids Research (2018). Accepted.
The TubR-centromere complex adopts a double-ring segrosome structure in Type III partition systems
53) Arroyo et al. Journal of Molecular Biology (2018). Accepted.
Supramolecular assembly of human pulmonary surfactant protein SP-D.
52) Madariaga-Marcos et al. Nanoscale Mar 1;10(9):4579-4590 (2018). doi: 10.1039/c7nr07344e.
Force determination in lateral magnetic tweezers combined with TIRF microscopy.
51) Vilhena JG et al. Journal of Physical Chemistry B Jan 18;122(2):840-846 (2018). doi:10.1021/acs.jpcb.7b06952. [Epub 2017 Oct 10].
Stick-Slip Motion of ssDNA Over Graphene.
50) Fisher GL et al. Elife Dec 15;6 (2017) pii: e28086. doi: 10.7554/eLife.28086.
The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere.
49) Marín-González*, Vilhena*, Perez and Moreno-Herrero. Proceedings of the National Academy of Sciences USA 114(27), 7049-7054 (2017). doi: 10.1073/pnas.1705642114.
Double stranded DNA and RNA under constant stretching forces: atomistic insights from microsecond-long molecular dynamics.
48) Fuentes-Pérez ME et al. Scientific Reports Feb 23; 7:43342. doi: 10.1038/srep43342 (2017).
TubZ filament assembly dynamics requires the flexible C-terminal tail.
47) Pastrana*, Carrasco* et al. Nucleic Acids Research 44(18), 8885-8896 Published Online Aug3 (2016).
Force and twist dependence of RepC nicking activity on torsionally-constrained DNA molecules
46) Ares et al. Nanoscale 8,11818-11826 (2016).
High resolution atomic force microscopy of double-stranded RNA
45) Gilhooly et al. Nucleic Acids Research 44(6), 2727-2741 Published Online Jan 13 (2016).
Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination
44) Gollnick et al. Small 11(11), 1273-1284 (2015), (Accepted, Oct 7, 2014). (cover article).
Probing DNA helicase kinetics with temperature controlled magnetic tweezers
43) Taylor*, Pastrana* et al. Nucleic Acids Research 43(2), 719-731 (2015) (Accepted, 28-Nov, 2014, Online 8 Jan 2015).
Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation
42) Torreira et al. Structure 23(1), 183-189 (2015), (Accepted, Nov, 2014).
Amyloid fibers of the bacterial prionoid RepA-WH1 recapitulate the dimer to monomer transitions at initiation of DNA replication
41) Wegrzyn et al. Nucleic Acids Research 42(12), 7807-7818 (2014).
Sequence-specific interactions of Rep proteins with ssDNA in the AT-rich region of the plasmid replication origin
40) Carrasco et al. DNA Repair 20, 119-129 (2014) (cover article).
Single molecule approaches to monitor the recognition and resection of double-stranded DNA breaks during homologous recombination
39) N. Laohakunakorn et al. Nano Letters 13 (11), 5141-5146 (2013).
A Landau-Squire Nanojet
38) C. Carrasco et al. Proceedings of the National Academy of Sciences USA 110 (28), E2562-2571 (2013).
On the Mechanism of Recombination Hotspot Sequence Scanning by a Bacterial Helicase-Nuclease
37) S. Hernández-Ainsa et al. ACSnano 7 (7), 6024-6031 (2013).
DNA Origami Nanopores for Controlling DNA Translocation
36) J. Camunas-Soler et al. ACSnano 7 (6), 5102-5114 (2013).
Electrostatic Binding and Hydrophobic Collapse of Peptide-Nucleic Acid Aggregates Quantified Using Force Spectroscopy
35) N.A.W. Bell et al. Lab on a Chip 13, 1859-1862 (2013).
Multiplexed ionic current sensing with glass nanopores
34) M.E. Fuentes-Perez et al. METHODS 60, 113-121 (2013).
AFM volumetric methods for the characterization of proteins and nucleic acids
33) E. Herrero-Galan et al. The Journal of the American Chemical Society 135(1), 122-131 (2013).
Mechanical identities of RNA and DNA double helices unveiled at the single-molecule level
32) F. Moreno-Herrero and J. Gomez-Herrero.
AFM: basic concepts
Chapter in book Atomic Force Microscopy in Liquid. Biological Applications
Arturo M. Baro & Ronald G. Reifenberger, Editors
Wiley-VCH (2012) Print ISBN: 978-3-527-32758-4.
31) M.E. Fuentes-Perez et al. Biophysical Journal 102, 839-848 (2012).
Using DNA as a fiducial marker to study SMC complex interactions with the Atomic Force Micrsocope
30) Yeeles JTP et al. Molecular Cell 42, 806-816 (2011).
Recombination hotspots and single-stranded DNA binding proteins couple DNA translocation to DNA unwinding by the AddAB helicase-nuclease
29) C.Carrasco and F. Moreno-Herrero Enclycopedia of Life Sciences DOI:10.1002/9780470015902.a0023173 (2011).
Magnetic Tweezers
28) S. Hormeno et al. Biophysical Journal 100, 1996-2006 (2011).
Mechanical Properties of High GoC-content DNA with A-type base-stacking
27) S. Hormeno et al. Biophysical Journal 100, 2006-2015 (2011).
Condensation prevails over B-A transition in the structure of DNA at low humidity"
26) T. van der Heijden et al. Nano Letters 7(4), 1112 (2007).
AFM tip-induced dissociation of RecA-dsDNA filaments
25) T. van der Heijden et al. Nano Letters 6(12), 3000-3002 (2006).
Comment on "Direct and real-time visualization of the disassembly of a single RecA-DNA-ATPgS complex using AFM imagin in fluid"
24) P.A. Wiggins et al. Nature Nanotechnology 1, 137-141 (2006).
High flexibility of DNA on short length scales probed by atomic force microscopy
23) F. Moreno-Herrero et al. Nucleic Acids Research 34(10), 3057-3066 (2006).
Structural analysis of hyperperiodic DNA from Caenorhabditis elegans
22) F. Moreno-Herrero et al. Nucleic Acids Research 33(18), 5945-5953 (2005).
Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion
21) F.Moreno-Herrero et al. Nature 437 (7057), 440-443 (2005).
Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon DNA binding
20) F. Moreno-Herrero et al. Biophysical Journal 88(1), 381A-381A Part 2 Suppl. S. (2005).
The interaction between Vaccinia topoisomerase IB and DNA studied with the atomic force microscope
19) J.A. Abels et al. Biophysical Journal 88(1), 570A Part 2 Suppl. S. (2005).
Single-molecule measurements of the persistence length of double-stranded RNA
18) J.A. Abels et al. Biophysical Journal 88(4), 2737-2744 (2005).
Single molecule measurements of the persistence length of double-stranded RNA
17) M. Diaz-Hernandez et al. Journal of Neoroscience 24(42), 9361-9371 (2004).
The stable component of Huntington's disease inclusions consist of amyloid-like huntingtin filaments that can be purified and that are susceptible to revert in vivo
16) F. Moreno-Herrero et al. European Polymer Journal 40(5), 927-932 (2004).
Jumping mode atomic force microscopy obtains reproducible images of Alzheimer paired helical filaments in liquids
15) F. Moreno-Herrero et al. Physical Review E 69, 031915 (2004).
Jumping Mode Scanning Force Microscopy: a tool for precise force control and high-resolution imaging in liquids
14) F. Moreno-Herrero et al. Biophysical Journal 86, 517-525 (2004).
Characterization by atomic force microscopy of Alzheimer paired helical filaments under physiological conditions
13) F. Moreno-Herrero et al. Ultramicroscopy 96, 167-174 (2003).
DNA height in Scanning Force Microscopy
12) F. Moreno-Herrero et al. Applied Surface Science 210, 22-26, (2003).
Jumping Mode Scanning Force Microscopy: a suitable technique for imaging DNA in liquids
11) F. Moreno-Herrero et al. Nanotechnology 14 (2), 128-133, (2003).
Topographic characterization and electrostatic response of M-DNA studied by Atomic Force Microscopy
10) F. Moreno-Herrero et al. Applied Physics Letters 81, 2620 (2002).
Scanning Force Microscopy Jumping and Tapping modes in liquids
9) C.Gómez-Navarro*, F. Moreno-Herrero* et al. Proceedings of the National Academy of Sciences USA 99 (13), 8484-8487 (2002).
Contactless experiments on individual DNA molecules show no evidence for molecular wire behavior
LINK
*Shared first authorship
8) C.Gómez-Navarro et al. Nanotechnology 13, 1-4 (2002).
Scanning force microscopy three-dimensional modes applied to the study of the dielectric response of adsorbed DNA molecules
7) T.de la Cera et al. Journal of Molecular Biology 319, 703-714 (2002).
Mediator factor Med8p interacts with the hexokinase 2: Implication in the glucose signalling pathway of Saccharomyces cerevisiae
6) C.Gómez-Navarro et al. Phantoms Newsletters 4, 4-6 (2002).
DNA, the miracle molecule
5) F. Moreno-Herrero et al. Journal of Alzheimer's Disease 3, 443-451 (2001).
Characterization by atomic force microscopy of tau polymers assembled in Alzheimer´s disease
4) F. Moreno-Herrero et al. Biochemical and Biophysical Research Communications 280, 151-157 (2001).
Imaging and mapping protein-binding sites on DNA regulatory regions with atomic force microscopy
3) P.J.de Pablo et al. Physical Review. Letters 85 (23), 4992-4995 (2000).
Absence of dc-conductivity in lambda DNA
2) F. Moreno-Herrero et al. Surface Science 453, 152-158 (2000).
The role of shear forces in scanning force microscopy: a comparison between jumping mode and tapping mode
1) F. Moreno-Herrero et al. FEBS Letters 459, 427-432 (1999).
Analisis by atomic force microscopy of Med8 binding to cis-acting regulatory elements of the SUC2 and HXK2 genes of Saccharomyces cerevisiae
