Clara Aicart Ramos graduated in Biochemistry in 2008 at the Universidad Complutense de Madrid. Then, she was granted with a FPU scholarship to do her PhD. She obtained her PhD in Biochemistry and Molecular Biology (Cum laude, 2009-2013) at the Universidad Complutense de Madrid under the supervision of Prof. J. I. Rodríguez Crespo on the study of mechanisms of regulation of the activity of Nitric Oxide Synthases and the characterization of the insect nuclear receptors of the E75 family. During her PhD, Clara enjoyed a research stay of three months at the University of California San Francisco under the supervision of Prof. P. Ortiz de Montellano. During her PhD she was also also involved in a collaboration project with the Colloidal and Supramolecular Chemistry group at the Universidad Complutense de Madrid in their research focused on vectorization of DNA by cationic liposomes and micelles. Her academic background has been awarded with the 2nd National Award on Biochemistry, the Special Award for Biochemistry degree and the Ph.D. Extraordinary Prize on Biochemistry by the Universidad Complutense de Madrid.
On March 2014, Clara moved to New York to perform a postdoctoral stay at Albert Einstein College of Medicine under the supervision of Prof. C. Rubin where she studied the role of dimerization of Protein Kinase D in the regulation of secretion and innate immunity of Caenorhabditis elegans. In a later short postdoctoral stay since November 2015 at the Universidad Complutense de Madrid, the research was focused on protein palmitoylation.
She joined Fernando’s group of Single-Molecule Biophysics of DNA-repair Nanomachines at CNB-CSIC in November 2016. She works full time for the ERC funded Mechan-of-Chromo Project since November 2016. Being expert on biochemistry and molecular biology, her role is to set-up and run the new molecular biology laboratory for the group, including the design and production of the required biomolecules for the experiments.
She has handled with several molecular genetics techniques, expression and purification of recombinant proteins in bacteria and in the baculovirus-infected insect cell system, protein characterization by different biochemical methods and mammalian cell cultures (maintenance, transfection, gene silencing, several assays). In addition she has worked with the model organisms Caenorhabditis elegans and Saccharomyces cerevisiae.